Table 4.
Brain regions in which anxiety types moderated habituation
| Region | Cluster size (mm3) | Direction of relationship | Mean z-value | Location | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| Anxious apprehension | ||||||
| L IFG (Broca's area, BA 45/46) | 1196 | ↓ | 2.30 | −51 | 28 | 13 |
| R SFG (BA 6/8) | 1844 | ↑ | −2.27 | 17 | 20 | 59 |
| M dACC (BA 24) | 1142 | ↑ | −2.27 | −1 | 1 | 43 |
| Anxious arousal | ||||||
| R MTG/ITG (BA 20/21) | 2188 | ↓ | 2.28 | 64 | −40 | −10 |
| M and R SFG (BA 6/8) | 1616 | ↓ | 2.14 | 8 | 22 | 58 |
| M Paracingulate (BA 6/8) | 1478 | ↓ | 2.30 | 2 | 35 | 40 |
| R MFG (DLPFC, BA 6/8/9) | 5149 | ↓ | 2.25 | 44 | 22 | 32 |
L, left; R, right; M, medial; SFG, superior frontal gyrus; MFG, middle frontal gyrus; IFG, inferior frontal gyrus; DLPFC, dorsolateral prefrontal cortex; MTG, middle temporal gyrus; ITG, inferior temporal gyrus; dACC, dorsal anterior cingulate cortex; BA, Brodmann's area. ↑, Higher questionnaire scores associated with increased activation over time; ↓, Higher questionnaire scores associated with decreased activation over time; Location, coordinates are for center of mass and are for ICBM152 2009a symmetrical space, with the x-axis moving from left to right.