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. Author manuscript; available in PMC: 2013 Dec 21.
Published in final edited form as: Nanoscale. 2013 Sep 17;5(21):10.1039/c3nr03121g. doi: 10.1039/c3nr03121g

Table 2.

Whole blood pharmacokinetic values of compounds 1, 2 and 3a

Compound Doseave (mg) AUC0→96 h (μg mL−1)h t1/22λ (h) CL (mL h−1) Vss (mL)
1 2.16 847 20.1 2.47 53.4
2 0.923 1020 16.0 0.797 10.4
3 0.989 1480 15.6 0.542 8.02
a

Noncompartmental modeling was used for the calculation of pharmacokinetic parameters based on the composite data in Fig. 2.