Fig. 2. Binding of DC8 expressing parasites to human brain microvascular endothelial cells (HBMEC).

Binding characteristics of IT4VAR20 expressing FCR3 parasites shown as a) median binding (percentiles: 10,25,75,90) of n=10 independent experiments in relation to the mean control binding in medium and b) triplicate measures in one representative experiment of three. Binding was measured with rEPCR (60 μg/ml or as indicated) and anti-receptor IgG (20 μg/ml) or anti-PfEMP1 IgG (500 μg/ml). P values for comparisons were evaluated using wilcoxon test for paired differences.