Figure 1. Chemoreflex function and selective carotid body denervation in CHF.
(A) Representative ventilatory recordings of the chemoreflex ventilatory response to acute hypoxia (FiO2 ~ 10%) in rats with and without CBD. (B) CBD abrogated the exaggerated hypoxic ventilatory response in CHF rats. VE: minute ventilation. *P<.05 vs. Sham, ***P<.001 vs. Sham, ++P<.01 vs. CHF, +++P<.001 vs. CHF. (Comparisons between groups at same FiO2.) Sham/Sham+CBD, n=6; CHF/CHF+CBD, n=8.