Table 1.

For 15 SNPs in HTR2A (chromosome 13q14-q21), the percentage of women who reported weight/shape concerns, binge eating and compensatory behaviors who also carry one or more copies of the minor allele (+) and those homozygous for the major allele (−) in 1534 European-American female twins aged 18–29 years.

SNP	Base-pair	Minor Allele Frequency#	Weight/Shape Concerns		Binge Eating		Compensatory Behaviors
			+	−	+	−	+	−
rs1923882	46309662	0.23 (A/G)	24.4	26.7	7.3	6.4	16.9*	21.2*
rs9567735	46317205	0.15 (G/A)	26.7	25.5	7.3	6.6	21.8	18.6
rs6561333%	46318313	0.45 (A/G)	24.8	25.8	5.6*	9.9*	19.8	19.5
rs2296972	46326472	0.28 (A/C)	24.1	27.4	5.0**	8.5**	19.9	19.1
rs9316233	46331356	0.18 (C/G)	24.6	26.4	7.3	6.5	19.1	19.5
rs1928042	46335217	0.24 (C/A)	26.1	25.5	6.8	6.8	18.8	19.9
rs582385	46343995	0.18 (G/A)	26.9	25.3	7.1	6.6	18.8	19.7
rs1928040	46345237	0.35 (A/G)	26.5	24.7	6.5	7.1	19.8	18.9
rs731779	46350039	0.21 (C/A)	24.0	26.8	6.1	7.2	20.3	19.0
rs985933	46353864	0.39 (A/G)	24.8	27.3	6.5	7.2	20.5	17.6
rs927544	46354052	0.30 (G/A)	25.4	26.3	6.3	7.3	20.6	18.3
rs9534505	46358745	0.09 (A/G)	23.3	26.3	6.3	6.9	18.8	19.4
rs4941573	46362858	0.42 (G/A)	25.30	26.8	6.9	6.6	19.4	19.7
rs1328685	46369891	0.10 (G/A)	24.1	26.2	7.8	6.5	19.4	19.5
rs4142900	46371551	0.48 (A/C)	25.0	28.0	6.3	8.0	19.0	20.7

^#Alleles presented as minor/major. Positions based on NCBI build 36.3; “+” carriers of minor allele; “−“ homozygous for major allele.

^*p-value less than 0.05

^**p-value less than 0.005;

^%only typed in the first round of genotyping; no longer supported by assay design, N=1039