Table 3.
Results of analyses using the Cox PH cure model with stepwise variable selection (α = 0.05).
Variables | Odds ratio (95% CI) | P value | Hazard ratio (95% CI) | P value |
---|---|---|---|---|
HR status | <0.001 | 0.019 | ||
Negative | 1 | 1 | ||
Positive | 0.30 (0.17, 0.52) | 2.83 (1.19, 6.73) | ||
ET therapy | Not selected | <0.001 | ||
No | 1 | |||
Yes | 0.05 (0.02, 0.13) | |||
Age | Not selected | 0.97 (0.95, 0.99) | 0.013 | |
Clinical stage | Not selected | 0.007 | ||
IIA/IIB/IIIA | 1 | |||
IIIB/IIIC | 1.90 (1.19, 3.03) | |||
Clinical response | 0.003 | 0.004 | ||
SD/PD | 1 | 1 | ||
PR | 0.82 (0.41, 1.65) | 0.44 (0.26, 0.74) | ||
CR | 2.25 (0.99, 5.07) | 0.60 (0.29, 1.25) | ||
HER2 status | 0.023 | 0.019 | ||
Negative | 1 | 1 | ||
Positive | 0.54 (0.31, 0.92) | 1.69 (1.09, 2.61) | ||
Histological grade | 0.044 | 0.042 | ||
1 and 2 | 1 | 1 | ||
3 | 0.59 (0.35, 0.98) | 1.58 (1.02, 2.45) | ||
Number of lymph node metastases | <0.001 | 0.002 | ||
0 | 1 | 1 | ||
1–3 | 0.43 (0.25, 0.74) | 1.15 (0.61, 2.13) | ||
≥4 | 0.10 (0.05, 0.19) | 2.21 (1.25, 3.90) |