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The weekly adequate relief (AR) among all eligible patients using the intention-to-treat principle, according to treatment group assignment. The response rate is the proportion of AR among patients in each group. The proportion of AR showed no statistically significant difference among 4 groups. AR: adequate relief, GJS: Gwakhyangjeonggisan, DUO: Duolac7S, GJS-P: placebo of Gwakhyangjeonggisan, DUO-P: placebo of Duolac7S, *P < 0.05.
