Table 3.
The change of 7 types of strains numbers, Firmicutes/Bacteroidetes ratio in feces, and IPI value among 4 groups between 0 week and 8 weeks.
| Variables | GJS-P+DUO-P (n = 13) |
GJS+DUO-P (n = 13) |
GJS-P+DUO (n = 10) |
GJS+DUO (n = 12) |
P value | |
|---|---|---|---|---|---|---|
| ΔN log10 (Mean ± SD)/1 g feces of bacterial species | B. longum | −0.016 ± 0.424 | −0.147 ± 0.203 | 0.302 ± 0.448 | −0.184 ± 0.198 | 0.695 |
| B. brevis | −1.120 ± 0.405 | −0.333 ± 0.282 | 1.850 ± 0.477 | 1.670 ± 0.485 | <0.001 | |
| B. lactis | −0.993 ± 0.357 | 0.177 ± 0.369 | 1.811 ± 0.381 | 2.060 ± 0.412 | <0.001 | |
| S. thermophilus | −0.168 ± 0.402 | −0.388 ± 0.320 | 0.802 ± 0.252 | 0.842 ± 0.270 | 0.01 | |
| L. rhamnosus | −0.553 ± 0.788 | 0.654 ± 0.678 | 2.478 ± 0.682 | 3.525 ± 0.592 | <0.001 | |
| L. plantarum | −1.338 ± 0.465 | −0.324 ± 0.538 | 1.528 ± 0.351 | 2.029 ± 0.463 | <0.001 | |
| L. acidophilus | −0.784 ± 0.601 | −0.537 ± 0.447 | 1.723 ± 0.550 | 1.790 ± 0.370 | <0.001 | |
| Firmicute/Bacteriodetes | 0.410 ± 0.149 | −0.139 ± 0.226 | 0.392 ± 0.313 | −0.050 ± 0.199 | 0.211 | |
|
| ||||||
| The change of IPI value | 0.136 ± 2.025 | −0.546 ± 1.642 | −1.190 ± 1.413 | −0.741 ± 1.980 | 0.398 | |
GJS: Gwakhyangjeonggisan, DUO: Duolac7S, GJS-P: placebo of Gwakhyangjeonggisan, DUO-P: placebo of Duolac7S, IPI (%): intestinal permeability index (Lactulose/mannitol).
The change of number of bacterial species was analyzed by one way-ANOVA and presented as ΔN log10 (mean ± SD)/1 g feces.
The change of intestinal permeability index is presented as percentage (%).