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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Am J Med Genet C Semin Med Genet. 2013 Oct 4;163(4):10.1002/ajmg.c.31375. doi: 10.1002/ajmg.c.31375

Fig 2. Prevention of Treacher Collins syndrome Craniofacial Anomalies.

Fig 2

Bone (alizarin red) and cartilage (alcian blue) stained E18.5 (A) Tcof1+/+, (B), Tcof1+/− and (C) Tcof1+/−; p53+/− mouse embryos demonstrating that suppressing p53 activity has the capacity in animal models to prevent the pathogenesis of craniofacial anomalies characteristic of Treacher Collins syndrome.