FIG 6 .
Virulence of the cor mutant is attenuated in mice. BALBc mice were infected with 102 CFU wild-type (WT) M. tuberculosis, the cor mutant, or the cor mutant complemented with cor via aerosol. (A) Ten mice per group were monitored over time for survival. By Kaplan-Meier analysis, differences between groups infected with the cor mutant and M. tuberculosis Erdman or the complemented strain are statistically significant. (B and C) Five mice per group were sacrificed, mouse lung (B) and mouse liver (C) were harvested and homogenized, and CFU were enumerated. *, P < 0.05 compared to WT (by the nonparametric Kruskal-Wallis test).