Skip to main content
. 2013 Dec 10;4(6):e00707-13. doi: 10.1128/mBio.00707-13

FIG 2 .

FIG 2 

Listeria and the intestinal microbiota slightly affect the intestinal miRNA expression pattern. (A) The 10 most highly expressed miRNAs (miR) in the small intestine of conventional (CV) and germfree (GF) mice uninfected or orally infected with L. monocytogenes for 24 h and 72 h (24 h p.i. and 72 h p.i.) were determined. In each list, the identity of each individual miR (miR id) is indicated, as well as its percentage (miR %) of the total miRs. (B) Relative expression levels of miR-21, miR-30d, miR-143, miR-148a, miR-192, miR-194, miR-200b, miR-200c, miR-215, and miR-378 in conventional (CV) and germfree (GF) mice orally infected with L. monocytogenes for 24 h and 72 h (24 h p.i. and 72 h p.i.). Shown are fold changes after standardization to the small nuclear RNA U6 and using uninfected CV and GF control mice as references. Data are represented as means with standard errors of the means (SEM) of values for individual mice (n ≥ 3 per group) from three independent experiments. Statistical tests were performed using a two-tailed Student’s t test. Asterisks indicate a value considered statistically significant (*, P < 0.05; **, P < 0.01; ***, P < 0.001); ns, nonsignificant difference.