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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: J Immunol. 2013 Oct 25;191(11):10.4049/jimmunol.1301604. doi: 10.4049/jimmunol.1301604

Figure 6. PGN+poly(I:C) induces apoptosis in the uterus and placenta via the extrinsic pathway.

Figure 6

Immunolocalization of Fas, panel A–B and J–K; FasL, panel D–E and M–N; FADD, panel G–H and P–Q; in uterus and placenta recovered from the control and PGN+poly(I:C) treated groups. Panels C, F, I and L, O, R show the immunostaining index score (ISIS) in uterus and placentas recovered from control and PGN+poly(I:C) treated groups. Panel W shows isotype controls. Western blot analysis of Fas, panel S and V in uterus and placenta; Luminex assay of FasL, panel T in uterus and placenta; western blot analysis of FADD with GAPDH loading control, panel U and V in uterus and placenta recovered from the control and PGN+poly(I:C) treated groups. N=4–6 each group and six sections per animal were analyzed. Error bars= ±SEM. **P≤0.01 Significant difference vs respective control. Original magnification: 400X.