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. Author manuscript; available in PMC: 2013 Dec 23.
Published in final edited form as: Gynecol Oncol. 2009 Aug 7;115(2):10.1016/j.ygyno.2009.06.038. doi: 10.1016/j.ygyno.2009.06.038

Table 4.

Multivariate Cox proportional hazards model to estimate the association between different perioperative CA-125 response categories and progression-free survival (PFS)

Parameter Hazard Ratio (95% CI) P
Optimal Cytoreduction*
        Increase versus ≥80% decline 4.20 (2.04-8.66) 0.0001
        0-49.99% decline versus ≥80% decline 2.61 (1.51-4.52) 0.0006
        50-79.99% decline versus ≥80% decline 1.91 (1.31-2.79) 0.0008
Suboptimal cytoreduction*
        Increase versus ≥80% decline 0.91 (0.37-2.24) 0.83
        0-49.99% decline versus ≥80% decline 1.31 (0.69-2.49) 0.41
        50-79.99% decline versus ≥80% decline 0.78 (0.43-1.41) 0.41

95% CI, Hazard Ratio Confidence Interval

*

Multivariate Cox proportional hazards model adjusted for taxane as part of chemotherapy treatment, number of chemotherapy cycles, ascites volume, preoperative CA-125 level, age, and surgeon effect.