Table II.
Patient characteristics and statistical analysis.
| Group | Total (54) | ||||
|---|---|---|---|---|---|
| G1 (16) | G2 (18) | G3 (20) | p* | ||
| Age (yrs), mean (SD); Range |
58.2 (6.32); 45-70 |
69.6 (9.41); 55-83 |
69.6 (6.8); 64-81 |
p < 0.01 | 64.7 (9.5); 45-83 |
| Gender, n (%) | |||||
| male | 12 (75) | 12 (66) | 16 (80) | p = 0.88 | 40 (74) |
| Female | 4 (25) | 6 (34) | 4 (20) | 14 (26) | |
| Tumour Site | 9 OC 7 OP |
12 OC 6 OP |
11 OC 9 OP |
p = 0.61 | 32 OC 22 OP |
| Primary Tumour | 12 | 15 | 3 | 30 | |
| Recurrent Tumour | 2 | 2 | 7 | 11 | |
| Second Primary | 2 | 1 | 10 | 13 | |
| pT | |||||
| 1 | - | - | 4 | p < 0.01 | 4 |
| 2 | 7 | 5 | 5 | 17 | |
| 3 | 8 | 9 | 8 | 25 | |
| 4a | 1 | 4 | 3 | 8 | |
| pN (10 G3 patients had no neck dissection) | |||||
| 0 | 4 | 8 | 2 | p = 0.07 | 14 |
| 1 | 2 | 2 | - | 4 | |
| 2a | 1 | - | - | 1 | |
| 2b | 5 | 6 | 3 | 14 | |
| 2c | 4 | 2 | 2 | 8 | |
| 3 | - | - | 3 | 3 | |
| Skin Paddle Surface (cm2) | |||||
| mean (SD) range |
44.7 (15.5) 20-63 |
22.7 (4.5) 18-40 |
44 (16.9) 32-56 |
p < 0.01 | 34.7 (15.9) 18-63 |
| Operating time, (h), mean (SD); range |
9.5 (1.6); 7-12.4 |
6.6 (0.8); 5.2-8 |
7.4 (0.9); 6.1-8.3 |
p = 0.14 | 8 (1.8); 5.2-12.4 |
| Blood loss (Hb g/dl), mean (SD); range | 3.25 (1.4); 1.1-6.2 |
2.6 (1); 0.4-3.5 |
3.6 (2.6); 1.7-5.5 |
p = 0.59 | 3.04 (1.4); 0.4-6.2 |
| Patients blood-transfused, n (%) | |||||
| Yes | 3 (19) | 3 (17) | 4 (20) | p = 0.96 | 10 (19) |
| No | 13 (81) | 15 (83) | 16 (80) | 54 (81) | |
| Tracheotomy closure, mean (days) | 6 (4.2); 3-9 |
7.4 (2.7); 4-11 |
7 (2.1); 5-10 |
p = 0.83 | 7.3 (2.8); 3-11 |
| Oral intake restoration, mean (days) | 14.8 (10); 8-40 |
11.5 (5.9); 6-25 |
12.6 (4.7); 9-18 |
p = 0.63 | 13.2 (7.9); 6-40 |
| Discharge, (days), mean (SD) range |
23.2 (7.5); 16-39 |
21.8 (12); 12-61 |
26.5 (9.9); 16-38 |
p = 0.63 | 23.2 (9.8); 12-61 |
| Diet score, n, mean (SD); range |
1.33 (0.4); 1-2 |
1.28 (0.4); 1-2 |
1.6 (0.7); 1-3 |
p = 0.29 | 1.42 (0.6); 1-3 |
| Speech score, mean, n | 1 (0); 1-1 |
1.07 (0.2); 1-2 |
1.2 (0.4); 1-2 |
p = 0.28 | 1.06 (0.2); 1-2 |
SD: Standard deviation;
ChT: Chemotherapy;
RT: Radiotherapy;
Hb: Haemoglobin;
OC: Oral Cavity;
OP: Oropharynx;
*
Differences in mean values among groups were tested with ANOVA, for categorical variables chi-square Pearson test was used.