Table 3.
Association between Helicobacter pylori infection and allele of interleukin 1β, interleukin 4, interleukin 8, CD14, tumor necrosis factor-α, tyrosine-protein phosphates non-receptor type 11 in Indonesian people n (%)
| Allele | H. pylori (+) n = 66 | H. pylori (-) n = 522 | OR1 | 95%CI |
| IL-1β T-31C | ||||
| T | 33 (50.0) | 247 (47.3) | ref | |
| C | 33 (50.0) | 275 (52.7) | 1.10 | 0.70-1.73 |
| IL-4 T-33C | ||||
| T | 46 (69.7) | 370 (70.9) | ref | |
| C | 20 (30.3) | 152 (29.1) | 0.95 | 0.58-1.56 |
| IL-8 T-251A | ||||
| T | 39 (59.1) | 310 (59.4) | ref | |
| A | 27 (40.9) | 212 (40.6) | 0.99 | 0.62-1.57 |
| CD14 C-159T | ||||
| C | 32 (48.5) | 261 (50.0) | ref | |
| T | 34 (51.5) | 261 (50.0) | 0.95 | 0.60-1.49 |
| TNF-α T-1031C | ||||
| T | 38 (57.6) | 345 (66.1) | ref | |
| C | 28 (42.4) | 177 (33.9) | 0.73 | 0.46-1.15 |
| PTPN11 G/A at intron 3 | ||||
| G | 49 (74.2) | 395 (75.7) | ref | |
| A | 17 (25.8) | 127 (24.3) | 0.94 | 0.56-1.57 |
1
Odds rate with CI adjusted for age and sex by logistic regression model. H. pylori: Helicobacter pylori; IL: Interleukin; PTPN11: Tyrosine-protein phosphates non-receptor type 11.