Table 1.
Baseline Demographic and Illness Characteristics
| Demographic and illness characteristics | Total (n=79) | Early responder (n=36) | Early nonresponder (n=43) | p value |
|---|---|---|---|---|
| Age, years, mean±SD |
15.2±2.8 |
14.5±3.3 |
15.8±2.4 |
0.034 |
| Postpubertal status, n (%) |
68 (86.1) |
28 (77.8) |
40 (93.0) |
0.10 |
| Sex male, n (%) |
46 (58.2) |
22 (61.1) |
24 (55.8) |
0.64 |
| Race, n (%) |
|
|
|
0.91 |
| Caucasian |
29 (36.7) |
13 (36.1) |
16 (37.2) |
|
| Black/African-American |
27 (34.2) |
14 (38.9) |
13 (30.2) |
|
| Hispanic |
11 (13.9) |
5 (13.9) |
6 (14.0) |
|
| Asian |
6 (7.6) |
2 (5.6) |
4 (9.3) |
|
| Other |
6 (7.6) |
2 (5.6) |
4 (9.3) |
|
| Inpatients, n (%) |
62 (78.5) |
30 (83.3) |
32 (74.4) |
0.34 |
| Number of past admissions, mean±SD |
0.2±0.6 |
0.1±0.5 |
0.3±0.6 |
0.27 |
| Socioeconomic status, mean±SD |
2.6±0.9 |
2.7±0.9 |
2.6±1.0 |
0.82 |
| Weight, kg, mean±SD |
57.6±16.2 |
57.3±18.3 |
57.8±14.2 |
0.89 |
| BMI %-tile, mean±SD |
54.5±30.9 |
58.3±32.4 |
52.3±29.6 |
0.32 |
| Weight status, n (%) |
|
|
|
0.31 |
| Underweight |
6 (7.6) |
3 (8.3) |
3 (7.0) |
|
| Normal weight |
56 (70.9) |
22 (61.1) |
34 (79.1) |
|
| Overweight |
6 (7.6) |
4 (11.1) |
2 (4.7) |
|
| Obese |
11 (13.9) |
7 (19.4) |
4 (9.3) |
|
| Primary diagnosis, n (%) |
|
|
|
0.92 |
| Psychotic disorder not otherwise specified |
50 (63.3) |
22 (61.1) |
28 (65.1) |
|
| Schizophrenia |
23 (29.1) |
11(30.6) |
12 (27.9) |
|
| Schizophreniform disorder |
3 (3.8) |
1 (2.8) |
2 (4.7) |
|
| Schizoaffective disorder |
2 (2.5) |
1 (2.8) |
1 (2.3) |
|
| Brief psychotic disorder |
1 (1.3) |
1 (2.8) |
0 (0) |
|
| CGI-S, mean±SD |
5.6±0.8 |
5.7±0.9 |
5.6±0.8 |
0.66 |
| CGAS, mean±SD |
34.0±8.8 |
33.6±8.1 |
34.2±9.3 |
0.78 |
| Psychiatric family history, n (%) | ||||
| Any psychiatric disorder |
33 (60.0) |
11 (50.0) |
22 (66.7) |
0.22 |
| Schizophrenia family history | ||||
| First degree relative |
2 (3.6) |
2 (9.1) |
0 (0) |
0.16 |
| Second degree relative |
12 (21.8) |
4 (18.2) |
8 (24.2) |
0.74 |
| Comorbidity, n (%) | ||||
| Attention-deficit/hyperactivity disorder |
10 (12.7) |
7 (19.4) |
3 (7.0) |
0.17 |
| Lifetime substance use disorder |
10 (12.7) |
5 (13.9) |
5 (11.6) |
1.00 |
| Anxiety disorder |
9 (11.4) |
5 (13.9) |
4 (9.3) |
0.73 |
| Disruptive behavior disordersa |
6 (7.6) |
4 (11.1) |
2 (4.7) |
0.40 |
| Obsessive compulsive disorder |
5 (6.3) |
2 (5.6) |
3 (7.0) |
1.00 |
| Pervasive developmental disorder |
3 (3.8) |
1 (2.8) |
2 (4.7) |
1.00 |
| Depressive spectrum disordersb |
3 (3.8) |
2 (5.6) |
1 (2.3) |
0.59 |
| Mental retardation | 4 (5.1) | 1 (2.8) | 3 (7.0) | 0.62 |
a
Disruptive behavior disorders=oppositional defiant disorder, conduct disorder, intermittent explosive disorder, impulse control disorder not otherwise specified.
b
Depressive spectrum disorders=major depressive disorder, depressive disorder not otherwise specified, adjustment disorder with depressed mood.
CGAS, Children's Global Assessment of Functioning Scale; CGI-S, Clinical Global Impressions-Severity.
Bolded p-values indicate p<0.05.