Table 3.
Predictive Value Analysis of Early Response at Week 4 for Ultimate Response at Weeks 8–12 (LOCF)
| Sample | Sensitivity | Specificity | Positive predictive value | Negative predictive value | p value of 2×2 table |
|---|---|---|---|---|---|
| Total sample (n=79) |
68.9% |
85.3% |
86.1% |
67.4% |
<0.0001 |
|
Subgroup analysis by diagnostic groups | |||||
| Schizophrenia/Schizoaffective disorder (n=28) |
83.3% |
81.3% |
76.9% |
86.7% |
0.0016 |
| Psychosis NOS/ Brief psychotic disorder (n=51) |
63.6% |
88.9% |
91.3% |
57.1% |
0.0004 |
|
Subgroup analysis by treatment history | |||||
| Antipsychotic-naïve (n=61) |
67.6% |
91.7% |
92.6% |
64.7% |
<0.0001 |
| Antipsychotic-non-naïve (n=18) | 75.0% | 70.0% | 66.7% | 77.8% | 0.15 |
LOCF=last-observation-carried-forward; NOS, not otherwise specified.
Bolded p-values indicate p<0.05.