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Plots are adjusted for age *p ≤ 0.05 for comparison of the mean Z score of the doxorubicin plus dexrazoxane group with zero. **p ≤ 0.05 for comparison of the mean Z score for the doxorubicin group with zero. ***p ≤ 0.05 for comparisons of mean Z scores between the doxorubicin and doxorubicin plus dexrazoxane groups.
Adapted with permission from [166].
