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Target specificity of CDE-096
| Inhibitor | Enzyme | IC50* (nM) |
| PAI-1 | uPA | 25 ± 4 |
| tPA | 30 ± 6 | |
| PAI-114–1B | uPA | 29 ± 3 |
| tPA | 27 ± 4 | |
| PAI-1glyco | uPA | 15 ± 2 |
| Murine PAI-1 | uPA | 19 ± 2 |
| Rat PAI-1 | uPA | 22 ± 2 |
| Porcine PAI-1 | uPA | 18 ± 1 |
| Antithrombin | α-Thrombin | >300,000 |
| α1-PI | Elastase | >300,000 |
Values represent measured IC50 values or the highest CDE-096 concentration tested.
