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Re-fusion events predict the residual proliferation potential of RS cells. The fate of individual giant HRS cells (n = 36–54) was determined by continuous tracking of HL cell lines KMH2, L428, and L1236. (A) Only cells with a distinct cell fate until the end of the observation period (death or division) were subjected to analysis. (B) Giant HRS cells were grouped by dependency of their origin, and cell fate was reassessed. (C) Highlighted proliferation potentials of fHRS and gHRS cells.
