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. 2013 Dec 2;110(51):20693–20698. doi: 10.1073/pnas.1310201110

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Fig. 3. — H19 represses its targets via the MBD1 protein. (A) Expression levels of the IGN in Mbd1^−/− samples were detected by RT-qPCR. The expression level in WT MEFs was set at 1, and histograms show modifications relative to this level (n = 4). (B) siRNA-mediated knockdown experiments of MBD1 in WT MEFs. The expression level in MEFs treated with a nonsilencing control was set at 1, and histograms show modifications relative to this level (n = 6). (C) siRNA-mediated knockdown experiments of H19 in Mbd1^−/− MEFs. The expression level in MEFs treated with a nonsilencing control was set at 1, and histograms show modifications relative to this level (n = 6).