Fig. 4.

Ligand-binding and dimerization abilities of Toll truncations. All constructs containing at least the N-terminal 399 residues are able to bind Spz C106 according to a range of biophysical techniques. White and gray triangles indicate VLR capping structures, black triangles native Toll N- and C-caps. The Spz construct is represented before and after TEV processing, which leaves an additional glycine residue at the N terminus of C106. The constructs Toll_N13–VLR and active Spz C106 have been used for crystallography.