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. 2013 Sep 11;39(2):361–369. doi: 10.1038/npp.2013.197

Figure 3.

Figure 3

Earlier work in rodents and primates established distinct roles for the basolateral amygdala (BLA) and centromedial amygdala (CMA) complexes that we confirmed here in humans. We found a divergent relationship in connectivity strengths (using Fisher's r to z transformation) of BLA and CMA with select target regions. Three target regions were identified in the main analyses (see Figure 2) as exhibiting differences in BLA connectivity between posttraumatic stress disorder (PTSD) and trauma-exposed control groups. Scatter plots in the combined sample (PTSD+Control) highlight the significant connectivity relationships of BLA (x-axis) and CMA (y-axis) with two of the three target regions: (a) left inferior frontal gyrus (L-IFG) (r=–0.482, p=0.001) shaded in turquoise and (b) the dorsomedial (dm) PFC (r=–.361, p=0.02) shaded in gold. This divergent connectivity relationship between BLA and CMA was not significantly modulated by PTSD (p-values >0.05).