Table 1. Activation Peaks for Regions where Baseline Connectivity was Associated with Treatment Response.

Seed	Region and broadman area	MNI coordinates			Peak z-score
		X	Y	Z
Anterior midcingulate	Positive correlation
	Medial frontal gyrus (R), (BA11, BA47, BA25, and BA32)	16	30	−24	3.3
	Subcallosal gyrus (L) (BA 24 and BA25) and medial frontal gyrus (L) (BA11)	−6	28	−18	3.2
	Medial frontal gyrus (L) and middle frontal gyrus (L)	−22	38	−20	3
	Negative correlation
	Putamen (R)	28	4	2	3.4
	Thalamus (R), medial dorsal N, and ventral lateral N	14	−12	8	3.2
	Thalamus (L), medial dorsal N, VLN, VPN, and putamen	−20	−8	8	3.5
	Hippocampus (R) and amygdala	24	−14	−14	2.9
Subgenual cingulate	Positive correlation
	Left paracingulate gyrus, medial frontal gyrus, (BA6, BA9, and BA32), and superior frontal gyrus (bi)	−8	34	28	3.7
	Left middle frontal gyrus (BA8 and BA9)	−32	14	38	3.6
	Right middle frontal gyrus and inferior frontal gyrus, (BA9)	44	18	28	3.2
	Negative correlation
	Right insula, claustrum, and putamen	38	2	−6	4
	Right parahippocampal gyrus and amygdala	20	−6	−16	3.9

Abbreviation: HAMD, Hamilton Depression Rating Scale.

Z-scores indicate the degree of correlation between connectivity and symptom improvement (HAMD reduction). Peaks are from significant clusters (p<0.05 corrected).