Figure 6.

(A and B) Pre-egress dynamic condition of iRBCs as represented by the outputs of the MeanRadius (A) and Circularity (B) filters. The filter traces were normalized by their means over the pre-egress period and are shown as a function of time before, during, and after egress. Q-type (black trace): quiescent condition; D-type (gray trace): dynamic condition. The sample shown is representative of the two conditions in the full dataset. The egress event is indicated by a sharp drop in all mean-normalized traces reflecting edge collapse. The residual signal/noise ratio post-egress results from edge points assigned to the cell center, thus reducing the mean radius and the variance in the mean radius (circularity).