Table 2.
hs-CPR < 4.26 | hs-CRP ≥ 4.26 | P value | |
---|---|---|---|
n = 38 | n = 31 | ||
Age (years) | 56.2 ± 13.7 | 59.0 ± 13.9 | 0.406 |
Gender (M/F) | 21/17 | 18/13 | 0.815 |
BMI (kg/m2) | 22.0 ± 3.4 | 22.0 ± 3.4 | 0.990 |
Smoking | |||
Never | 30 | 25 | 0.862 |
Ex/current | 8 | 6 | |
PFT | |||
FVC (L) | 2.25 ± 0.81 | 1.85 ± 0.71 | 0.034 |
FVC (%) | 72.5 ± 16.4 | 61.1 ± 21.0 | 0.014 |
FEV1 (L) | 1.69 ± 0.74 | 1.34 ± 0.59 | 0.038 |
FEV1 (%) | 67.6 ± 21.4 | 56.6 ± 23.5 | 0.046 |
FEV1/FVC (%) | 73.5 ± 11.0 | 71.3 ± 10.4 | 0.401 |
Total IgE (KU/L) | 137.8 ± 320.3 | 170.9 ± 490.6 | 0.737 |
ECP (mcg/L) | 17.5 ± 17.8 | 24.5 ± 36.7 | 0.304 |
6 MWT | |||
Rest O2 sat (%) | 96.4 ± 1.6 | 93.5 ± 4.4 | 0.001 |
Lowest O2 sat (%) | 87.7 ± 6.4 | 85.2 ± 10.2 | 0.237 |
ΔO2 sat (%) | 8.7 ± 6.1 | 8.4 ± 7.4 | 0.816 |
Walk distance (meters) | 469.3 ± 78.2 | 436.1 ± 104.1 | 0.136 |
HRCT scores | 21.7 ± 9.8 | 28.1 ± 13.1 | 0.004 |
Bacterial colony | |||
Ps. aeruginosa | 6 | 11 | 0.115 |
Others | 8 | 4 | |
Normal flora/no growth | 24 | 16 | |
Hospitalizations before recruitment (times/year) | |||
<2 | 35 | 21 | 0.01 |
≥2 | 3 | 10 |
Abbreviations: hs-CRP: high-sensitivity C-reactive protein, PFT: pulmonary function test, IgE: immunoglobulin E, ECP: eosinophilic cationic protein, 6 MWT: 6-minute walk test, ΔO2 sat (%): oxygenation difference between rest and lowest during 6-minute walk test, and HRCT: high-resolution computed tomography.