Skip to main content
. Author manuscript; available in PMC: 2013 Dec 24.
Published in final edited form as: Curr HIV Res. 2012 Apr;10(3):218–227. doi: 10.2174/157016212800618093

Figure 3. C. trachomatis infection of A2EN cells increases surface expression of HIV-1 primary and co-receptors.

Figure 3

A2EN cells were mock-infected or infected for 24 hours with C. trachomatis serovar D at levels promoting 90% infection. Cells were then immunostained for HIV receptors and co-receptors and analyzed by flow cytometry. C. trachomatis infection increased CCR5, CXCR4 and GalCer cell surface expression in a subpopulation of cells. CD4 was not detected on A2EN cells nor was it upregulated by C. trachomatis infection. Experiment is representative of 3 replicates. Legend: dashed line-isotype control; solid line – mock infected; filled histogram- C. trachomatis serovar D-infected.