Skip to main content
. 2014 Jan 8;34(2):506–514. doi: 10.1523/JNEUROSCI.2352-13.2014

Figure 4.

Figure 4.

a, Profile of hippocampal ACh efflux (percentage of baseline average; mean ± SEM) in PBS- and GAT1-SAP-treated animals; inset displays average basal hippocampal ACh efflux (fmol) in both groups. MSDB GAT1-SAP treatment did not change basal hippocampal ACh efflux. Both sham and GAT1-SAP groups had an increase in maze-evoked hippocampal ACh efflux (M samples) above their own baseline (B samples). In addition, MSDB GAT1-SAP treatment reduced maze-evoked hippocampal ACh efflux as compared with PBS animals (A samples = post-maze phase). b, Behavioral data (mean ± SEM) over 10 consecutive days of DNMTP training in both PBS- and MSDB GAT1-SAP-treated animals. Intraseptal GAT-SAP impaired DNMTP performance compared with PBS animals. GAT1-SAP animals did not significantly increase their choice accuracy over 10 d of training.