Mild preeclampsia |
New onset of sustained elevated blood pressure after 20 weeks’ gestation in a previously normotensive woman (≥140 mm Hg systolic or ≥90 mm Hg diastolic on at least 2 occasions 6 hours apart
Proteinuria of at least 1+ on a urine dipstick or ≥300 mg in a 24 hour urine collection after 20 weeks’
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Severe preeclampsia (above criteria plus any of the items listed) |
Blood pressure ≥160 mmHg systolic or ≥110 mmHg diastolic
Urine protein excretion of at least 5 grams in a 24 hour collection
Neurologic disturbances (visual changes, headache, seizures, coma)
Pulmonary edema
Hepatic dysfunction (elevated liver transaminases2 or epigastric pain)
Renal compromise (oliguria or elevated serum creatinine concentration, ≥ 1.2 is considered abnormal in women with no history of renal disease)
Thrombocytopenia
Placental abruption, fetal growth restriction, or oligohydramnios
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Eclampsia |
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Superimposed preeclampsia |
sudden and sustained increase in blood pressure with or without substantial increase in proteinuria.
new onset proteinuria (≥300 mg in a 24 hour protein collection) in a woman with chronic hypertension and no proteinuria prior to 20 weeks’*
sudden increase in proteinuria or a sudden increase in blood pressure in a woman with previously well controlled hypertension in a women with elevated blood pressure and proteinuria prior to 20 weeks of gestation*
Thrombocytopenia, abnormal liver enzymes, or a rapid worsening of renal function
*Precise diagnosis is often challenging and high clinical suspicion is warranted given the increase maternal and fetal/neonatal risks associated with superimposed preeclampsia**
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HELLP syndrome |
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Gestational hypertension |
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