Skip to main content
. 2013 Dec 2;124(1):273–284. doi: 10.1172/JCI70422

Figure 5. Large platelet thrombi are observed throughout the TD of Prox1+/– and Itga9–/– animals.

Figure 5

(A) Representative LVVs and lymphatic valves in Prox1+/– and Itga9–/– mice, which had impaired valve development. Valve rudiments are labeled and/or denoted by arrows. (B) Platelet-containing thrombi were observed in the TD adjacent to the SV in E17.5 Prox1+/– embryos. (C) Platelet-containing thrombi were observed next to the LVV and in the TD adjacent to the SV in E17.5 Itga9–/– embryos. (D) Platelet-containing thrombi extended to the proximal TD in the chest of E17.5 Prox1+/– and Itga9–/– embryos. Dotted outlines denote vessel walls. Scale bars: 50 μm.