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. 2013 Dec 8;4:43–54. doi: 10.1016/j.fob.2013.12.001

Fig. 2.

Fig. 2

Specificity of substrate 3144-AMC for circulating FAP. FAP activity was assayed in 1 μl of plasma from (A) mice, (n = 3–6) from four genetic backgrounds and (B) healthy adult humans (FAP+/+, n = 5), a heterozygous FAP activity-deficient individual (FAP+/−) and two separate homozygous individuals (FAP−/− 1, FAP−/− 2). FAP activity was expressed as pmol AMC released from substrate 3144-AMC/min/ml. Horizontal bars are means and error bars depict SEM.