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Percent change from baseline in renal vascular resistance for peripheral arterial disease (PAD) patients without and with ascorbic acid (AA) during 4 min of mild, rhythmic, plantar flexion exercise of increasing intensity (0.5–2 kg) with their most affected leg. Age-matched, healthy controls’ (CON) responses to exercise with their first leg are shown for reference. Treat, treatment; Int, interaction. *Significantly different from PAD-most at specific time point (P < 0.05).
