Table 4.
Surgical management of ipsilateral breast tumor recurrences.
Case no. | Date of surgery | Time to IBTR (yrs) | Location | ASTRO criteria | Surgical management | Radiation therapy | Follow-up time (yrs) | Disease status |
---|---|---|---|---|---|---|---|---|
22 | 2005 | 3.99 | Elsewhere | ER negative, close margin | Mastectomy | No | 5.21 | NED |
44 | 2005 | 3.13 | Elsewhere | ER negative | Mastectomy | No | 5.33 | NED |
50 | 2005 | 5.83 | Local | Age 50–59, DCIS ≤ 3 cm, and ER negative | Segmental resection | Noa | 5.81 | NED |
71 | 2006 | 2.64 | Elsewhere | Age < 50, close margin, and DCIS ≤ 3 cm | Mastectomy | No | 5.16 | DOD |
91.1b | 2007 | 3.82 | Elsewhere | ER negative, close margin, and tumor size 2.1–3.0 cm | Segmental resection | Noc | 3.95 | NED |
107 | 2006 | 1.45 | Elsewhere | Positive margin, multifocal 2.1–3.0 cm | Segmental resection | Yes | 4.52 | NED |
147 | 2007 | 2.73 | Elsewhere | Close margin | Segmental resection | Yesd | 3.50 | NED |
208 | 2009 | 1.21 | Elsewhere | Close margin, age 50–59, and DCIS ≤ 3 cm | Segmental resection | Noc | 1.56 | NED |
ER: estrogen receptor, NED: no evidence of disease, DCIS: ductal carcinoma in situ, and DOD: dead of disease.
aPatient is currently receiving chemotherapy. Decision for radiation was undetermined at the completion of the study.
bPatient tested positive for deleterious mutation in BRCA gene following recurrence.
cPatient declined radiation therapy.
dRecurrence treated with APBI via balloon catheter brachytherapy.