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. 2013 Nov 18;31(36):4529–4535. doi: 10.1200/JCO.2013.49.0086

Fig 3.

Fig 3.

(A) Overall survival (OS) curves against response categories. The median OS of the patients achieving at least a complete response (CR; n = 146) was 109 months (9 years; 95% CI, 94 to not reached [NR]) compared with 64 months (5.3 years; 95% CI, 53 to 78 months), 59 months (4.9 years; 95% CI, 50 to 86 months), 56 months (4.6 years; 95% CI, 40 months to NR), respectively, for those achieving very good partial response (VGPR; n = 151), partial response (PR; n = 109), and stable disease (SD; n = 21). Patients with progressive disease (PD) survived for a median of 9 months (0.8 years; 95% CI, 5 to 88 months; P < .001). (B) OS of the patients achieving varying degrees of CR. Those with stringent complete response (sCR; n = 109) had a marked improvement in OS (median OS, NR; 95% CI, NR to NR) compared with the patients achieving CR (n = 37; median OS, 81 months; 95% CI, 37 to 109 months) or near complete response (nCR; n = 91; median OS, 60 months; 95% CI, 47 to 78). The 5-year OS is 80%, 53%, and 47%, for patients achieving sCR, CR, and nCR, respectively (P < .001).