Table 1.

Patient Characteristics

Parameter	No. of Patients*	%	Median	Range
Age at transplantation, years	445		59	29-76
≥ 65		25
Creatinine at transplantation, mg/dL	445		1	0.4-10.1
PCLI at transplantation, %	442		0	0-11
Patients with PCLI ≥ 3%		7
LDH, U/L	431		189	158-230†
Patients with abnormal LDH (> 222 U/L)		29
CRP, mg/L	425		0.4	0.3-1.3†
Serum β2-microglobulin, μg/mL	442		2.5	1.1-57
Serum creatinine, mg/dL			1	0.4-10.1
≥ 2		7
Durie-Salmon stage at diagnosis	435
1		0
2a		34
2b		3
3a		57
3b		6
Cytogenetics	441
Abnormal cytogenetics		15
Patients with bone disease	445	85
ECOG performance status < 2	441	91
Time from diagnosis to ASCT, months	445		6	1.5-12
Pretransplantation response	445
sCR	7	2
CR	19	4
nCR	29	7
VGPR‡	51	11
PR	207	47
SD	96	22
PD	36	8

Abbreviations: ASCT, autologous stem-cell transplantation; CR, complete response; CRP, C-reactive protein; ECOG, Eastern Cooperative Oncology Group; LDH, lactate dehydrogenase; nCR, near complete response; PCLI, plasma cell labeling index; PD, progressive disease; PR, partial response; sCR, stringent complete response; SD, stable disease; VGPR, very good partial remission.

^*Total No. of patients for whom data were available at transplantation.

^†Interquartile range.

^‡Excluding patients in nCR.