Table 1.
Characteristic | No Cancer |
Lung Cancer |
Total |
P* | |||
---|---|---|---|---|---|---|---|
No. | % | No. | % | No. | % | ||
Age, years | .036† | ||||||
50-54 | 234 | 95.90 | 10 | 4.10 | 244 | 10.38 | |
55-59 | 443 | 96.72 | 15 | 3.28 | 458 | 19.49 | |
60-64 | 726 | 95.53 | 34 | 4.47 | 760 | 32.34 | |
65-69 | 568 | 93.57 | 39 | 6.43 | 607 | 25.83 | |
≥ 70 | 266 | 94.66 | 15 | 5.34 | 281 | 11.96 | |
Sex | .020 | ||||||
Male | 1,242 | 96.13 | 50 | 3.87 | 1,292 | 54.98 | |
Female | 995 | 94.05 | 63 | 5.95 | 1,058 | 45.02 | |
BMI | .016† | ||||||
Underweight (< 18.5 kg/m2) | 20 | 95.24 | 1 | 4.76 | 21 | 0.88 | |
Normal (18.5-24.9 kg/m2) | 803 | 93.59 | 55 | 6.41 | 858 | 36.51 | |
Overweight (25-29.9 kg/m2) | 1,031 | 96.18 | 41 | 3.82 | 1,072 | 45.62 | |
Obese (≥ 30 kg/m2) | 383 | 95.99 | 16 | 4.01 | 399 | 16.98 | |
Personal history of cancer | .112 | ||||||
No | 2,095 | 95.36 | 102 | 4.64 | 2,197 | 93.77 | |
Yes | 135 | 92.47 | 11 | 7.53 | 146 | 6.23 | |
Family history of cancer | .353 | ||||||
No | 1,458 | 95.54 | 68 | 4.46 | 1,526 | 66.12 | |
Yes | 740 | 94.63 | 42 | 5.37 | 782 | 33.88 | |
Pneumonia | .037 | ||||||
No | 1,648 | 95.76 | 73 | 4.24 | 1,721 | 73.42 | |
Yes | 583 | 93.58 | 40 | 6.42 | 623 | 26.58 | |
Emphysema | .423 | ||||||
No | 2,091 | 95.26 | 104 | 4.74 | 2,195 | 93.76 | |
Yes | 137 | 93.84 | 9 | 6.16 | 146 | 6.24 | |
Smoking status | .489 | ||||||
Former smoker | 871 | 95.61 | 40 | 4.39 | 911 | 38.77 | |
Current smoker | 1,366 | 94.93 | 73 | 5.07 | 1,439 | 61.23 | |
Race/ethnicity | .674† | ||||||
White | 2,175 | 95.14 | 111 | 4.86 | 2,286 | 97.65 | |
Asian | 22 | 95.65 | 1 | 4.35 | 23 | 0.98 | |
Aboriginal | 7 | 100 | 0 | 0 | 7 | 0.30 | |
Black or African Canadian | 12 | 92.31 | 1 | 7.69 | 13 | 0.56 | |
Other | 12 | 100 | 0 | 0.00 | 12 | 0.51 | |
Education | .936† | ||||||
8th grade or less | 63 | 94.03 | 4 | 5.97 | 67 | 2.85 | |
9th to 11th grade | 288 | 94.12 | 18 | 5.88 | 306 | 13.02 | |
High school graduate | 585 | 96.22 | 23 | 3.78 | 608 | 25.87 | |
Technical/vocational school | 239 | 94.09 | 15 | 5.91 | 254 | 10.81 | |
Associate's degree/some college | 428 | 94.48 | 25 | 5.52 | 453 | 19.28 | |
Bachelor's degree | 401 | 96.63 | 14 | 3.37 | 415 | 17.66 | |
Advanced degree | 233 | 94.33 | 14 | 5.67 | 247 | 10.51 | |
FEV1 ratio of predicted | 2,220 | 111 | 2,331 | .0034‡ | |||
Mean | 0.82 | 0.77 | 0.82 | ||||
SD | 0.18 | 0.19 | 0.18 | ||||
Median | 0.83 | 0.77 | 0.83 | ||||
IQR | 0.71-0.94 | 0.67-0.86 | 0.71-0.94 | ||||
Range | 0.15-1.68 | 0.27-1.36 | 0.15-1.68 | ||||
Pro-SFTPB, ng/mL | 2,193 | 112 | 2,305 | < .001‡ | |||
Mean | 43.5 | 75.0 | 45.1 | ||||
SD | 42.1 | 64.5 | 43.9 | ||||
Median | 30.7 | 54.2 | 31.6 | ||||
IQR | 16.5-54.3 | 30.8-99.1 | 16.9-55.7 | ||||
Range | 1.2-426.9 | 10.0-344.4 | 1.2-426.9 | ||||
No. of cigarettes smoked per day | 2,237 | 113 | 2,350 | .8943‡ | |||
Mean | 24.68 | 24.84 | 24.69 | ||||
SD | 10.51 | 12.51 | 10.61 | ||||
Median | 25 | 25 | 25 | ||||
IQR | 20-25 | 20-25 | 20-25 | ||||
Range | 1-100 | 5-100 | 1-100 | ||||
Smoking duration, years | 2,235 | 112 | 2,347 | .0012‡ | |||
Mean | 43.97 | 45.91 | 44.06 | ||||
SD | 5.87 | 6.06 | 5.89 | ||||
Median | 44 | 46.5 | 44 | ||||
IQR | 40-48 | 42-50 | 40-48 | ||||
Range | 11-69 | 27-60 | 11-69 | ||||
Time since quitting smoking, years | 2,237 | 113 | 2,350 | .9128‡ | |||
Mean | 17.85 | 17.62 | 17.84 | ||||
SD | 21.29 | 21.71 | 21.31 | ||||
Median | 0 | 0 | 0 | ||||
IQR | 0-41 | 0-41 | 0-41 | ||||
Range | 0-61 | 0-55 | 0-61 |
Abbreviations: BMI, body mass index; FEV1 ratio of predicted, forced expiratory volume in one second % predicted; IQR, interquartile range; pro-SFTPB, pro–surfactant protein B; SD, standard deviation.
Fisher's exact test.
Nonparametric test.
Satterthwaite's unequal variance t test.