Table 1.

Relationships between Sox2 and properties of cancer cells

Cases	Multiple roles of Sox2 in cancer cells	Types of cancer	References
1	Promotes proliferation and growth	Lung and esophageal SCCs	[10]
2	Promotes Cellular migration	Lung SCCs	[11]
3	Promotes Cellular migration	Colorectal cancer	[31]
4	Cancer stemness and chemoresistant	Glioma	[3]
5	Promotes proliferation and tumorigenicity	Glioblastoma Tics	[23]
6	Increases anti-apoptotic property and promotes tumorigenesis	Prostate cancer	[28]
7	Invasion and migration	Glioma and BTSCs (Brain tumor stem cells)	[32]
8	Metastases	Colon cancer	[34]
9	Invasion	Gastric cancer	[33]
10	Growth and metastasis	Lung cancer	[29]
11	Chemoresistance	HNSCC	[25]
12	Proliferation and apoptosis	Prostate cancer	[30]
13	Tumorigenesis	Lung cancer	[35]
14	Proliferation	SCLC	[14]
15	Proliferation and colony formation	LN229 GBM cells	[36]
16	Proliferation and tumorigenesis	Breast cancer	[43]
17	Proliferation and colony formation	Breast cancer	[50]