Figure 1. Antiproliferative effects of posaconazole and itraconazole on Leishmania amazonensis. L. amazonensis promastigotes (A, B) and intracellular amastigotes (C, D) were treated with posaconazole (POSA) (A, C) or itraconazole (ITZ) (B, D) to evaluate the parasite growth.

The arrows indicate the time of the addition of the drugs at the indicated concentrations. The results were plotted as the mean of three independent experiments and the bars represent the standard deviation.