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. 2013 Dec 20;8(12):e84226. doi: 10.1371/journal.pone.0084226

Table 3. Case-control association analysis of 5 variants using 1,074 chronic hepatitis C cases and 1,073 healthy controls.

Allele Case
Control
HWE-pa
Protective AF
SNP [1/2] 11 12 22 11 12 22 Case Control Case Control ORb (95%CI) P c
rs8099917 G/T 15 235 824 10 188 875 0.704 0.978 0.877 0.903 0.76 (0.63-0.92) 5.53E-03
rs12979860 T/C 16 244 814 11 194 868 0.637 0.965 0.872 0.899 0.76 (0.63-0.92) 4.08E-03
ss469415590 ΔG/TT 16 244 814 11 192 870 0.637 0.911 0.872 0.900 0.75 (0.62-0.91) 2.96E-03
rs9275572 T/C 166 492 416 112 459 502 0.305 0.641 0.616 0.682 0.75 (0.66-0.85) 9.64E-06
rs1130380 C/G 120 433 521 172 478 423 0.039 0.060 0.313 0.383 0.73 (0.65-0.83) 3.38E-06

AF; allele frequency, OR; odds ratio, CI; confidence interval.

a P value of Hardy-Weinberg equilibrium test. bOdds ratio of protective allele. c P value of Cochran-Armitage trend test.