Table 2. Pulmonary leukocytes in FI-RSV and G-A2 peptide vaccinated mice 5 days after RSV challenge a .
Phenotype | FI-A2+ A2 (x103) | FI-A2+G-A2 +A2 (x103) | |
---|---|---|---|
% Reduction | |||
CD3 | 146.1 + 20.2 | 63.7 + 16.3 | 56 |
B220 | 27.1+3.7 | 14.9 + 3.8 | 45 |
DX5 | 172.8+ 2.4 | 8.6 + 2.2 | 95 |
CD11b | 55.9 + 7.7 | 26.7 + 6.8 | 52 |
RB6-8C5 | 31.1 + 4.3 | 21.1 + 5.4 | 32 |
a Data represent the mean total BAL cells expressing CD3 (T cell marker), CD45R/B220 (B cell marker), DX5, (NK cell marker), CD11b (macrophage cell marker) or RB6-8C5 (PMN cell marker) from mice vaccinated with FI-A2 alone or with FI-A2 and G-A2 peptide, five days after RSV A2 challenge. The total number of BAL cells expressing a particular phenotype was determined by multiplying the mean total number of BAL cells by the mean percentage of cells expressing that phenotype. Boldface values indicate a significant decrease (p<0.05) in the number of BAL cells expressing a particular phenotype with addition of the G-A2 to FI-A2 vaccination.