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. 2013 Dec 23;8(12):e82191. doi: 10.1371/journal.pone.0082191

Table 1. Effects of multi-unit and single-unit HFS on glutamatergic unitary synaptic responses in the SNr.

HFS type Parameter Control HFS
Average ±SE Average ±SE N %Change p
Multi-unit FV in STN (µV) 835,08 185,43 861,25 285,79 8 none ns
FV in SNr (µV) 673,51 154,31 589,44 135,59 9 none ns
Multi-unit uEPSC occlusion-positive
Amplitude (pA) 23,26 3,15 5,88 1,14 9 −75 <0.001
PPR 0,84 0,09 1,36 0,20 9 63 0,022
CV (%) 53,97 6,07 179,24 22,18 9 232 <0.001
Success rate (%) 86,53 3,57 33,60 6,75 9 −61 <0.001
Multi-unit uEPSC occlusion-negative
Amplitude (pA) 46,27 7,58 20,10 4,03 27 −57 <0.001
PPR 0,86 0,06 1,30 0,12 27 52 <0.001
CV (%) 29,64 5,31 78,00 24,09 27 163 0,035
Success rate (%) 89,86 1,87 56,97 5,92 27 −37 <0.001
Multi-unit uEPSC occlusion-negative
Failures excluded
Amplitude (pA) 42,07 8,18 28,11 5,07 15 −33 0,002
PPR 0,83 0,06 1,04 0,06 15 25 0,002
CV (%) 36,67 2,72 38,46 2,72 15 none ns
Multi-unit uEPSC occlusion-negative
GABA(B) block
Amplitude (pA) 55,66 14,32 37,56 7,50 11 −33 0,070
PPR 0,95 0,10 1,07 0,15 11 12 ns
CV (%) 0,51 0,07 0,84 0,29 11 63 ns
Success rate (%) 89,54 3,75 78,63 8,64 11 −12 ns
Single-unit uEPSC
Amplitude (pA) 68,69 11,86 26,51 5,28 9 −61 0,001
PPR 0,91 0,09 1,09 0,06 8 20 0,033
CV (%) 41,09 5,29 61,02 5,76 8 49 0,007
Success rate (%) 93,89 2,63 58,89 10,79 9 −37 0,011