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. 2013 Dec 23;8(12):e83372. doi: 10.1371/journal.pone.0083372

Figure 5. Model for the dynamics of a minimal ceRNA network.

Figure 5

The expression of three proteins (Proteins 1, 2, and 3) is controlled by the same miRNA. Transcription factors (TF) only promote, with or without cooperativity mediated by their oligomerization, the synthesis of messenger RNA 1. The different messenger RNAs (RNAs 1, 2, 3) can form inhibitory complexes (RNA1i, RNA2i, RNA3i) with the miRNA, which prevent them to encode the synthesis of their respective protein.