Table 3. Summary of binding data.

	Φ*	kass (M−1s−1)	kdiss (s−1)	Kd (nM)	t1/2 (min)
U-insertion
w/o PEG	0	3.3×105	2.0×10−3	6.4	5.8
25% (w/v) PEG400	0.9	7.5×105	9.0×10−3	12.0	1.3
20% (w/v) PEG2000	3.3	0.4×105	0.6×10−3	13.4	20.6
U-deletion
w/o PEG	0	4.7×105	3.0×10−3	6.6	3.9
25% (w/v) PEG400	0.9	5.5×105	10.0×10−3	18.0	1.2
20% (w/v) PEG2000	3.3	0.6×105	0.9×10−3	12.6	13.6

k_ass, k_diss, K_d and t_1/2 of 20 S editosomes to U-insertion and U-deletion mRNA/gRNA hybrid RNAs at semidilute (Φ/Φ* = 0.9) and crowded (Φ/Φ* = 3.3) solvent conditions.