Table 3. Diagnostic accuracy for detecting coronary stenosis with > 70% lumen diameter reduction.

	Sensitivity	Specificity	PPV	NPV
HPA-based MBF cut-off (138.5 ml/100 g/min)	47/77, 61% (49.2-71.7%)	245/276, 89% (84.3-92.1%)	47/78, 60% (48.5-71%)	245/275, 89% (86.4-92.4%)
ROC-based MBF cut-off (174.5 ml/100g/min)	68/77, 88% (78.5-94.2%)	188/276, 68% (62.2-73.5%)	68/156, 44% (35.7-51.8%)	188/197, 95% (91.2-97.7%)

HPA-based MBF cut-off (138.5 ml/100g/min): myocardial blood flow cut-off value for detecting the quantitative transmural extent of hypoperfusion area (HPA). ROC-based MBF cut-off (174.5 ml/100g/min): myocardial blood flow cut-off value for detecting severe coronary artery stenosis (> 70%). PPV and NPV: positive and negative predictive values. Data are expressed as n/N, %, 95% confidence interval.