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. 2013 Dec 23;8(12):e83950. doi: 10.1371/journal.pone.0083950

Table 4. Diagnostic accuracy for detecting coronary stenosis with > 50% lumen diameter reduction.

Sensitivity Specificity PPV NPV
HPA-based MBF cut-off (193.5 ml/100 g/min) 160/203, 79% (72.4-84.1%) 124/150, 83% (75.4-88.2%) 160/186, 86% (80.0-90.5%) 124/167, 74% (66.8-80.6%)
ROC-based MBF cut-off (184.5 ml/100g/min) 152/203, 75% (68.2-80.6%) 131/150, 87.3% (80.7-92.0%) 152/171, 89% (83.0-93.0%) 131/182, 72% (64.8-78.2%)

HPA-based cut-off MBF (193.5 ml/100g/min): myocardial blood flow cut-off value for excluding non-HPA. ROC-based MBF cut-off (184.5 ml/100g/min): myocardial blood flow cut-off value for detecting significant coronary artery stenosis (> 50%). PPV and NPV: positive and negative predictive values. Data are expressed as n/N, %, 95% confidence interval.