Table 4.
Pat. no | Cardinal symptoms | Non-autistic symptoms | Pre-CARS | Age of treatment initiation in years | Post-CARS 6 months after treatment initiation | Cardinal symptoms 6 months after treatment initiation |
---|---|---|---|---|---|---|
1 | Hyperactivity, attention deficit, not responding to verbal cues, no speech, compulsive behavior, preoccupation with parts of objects, abnormal sleep | Pathologic EEG | 41 | 3,5 | 21 | No symptoms |
2 | Hyperactivity, attention deficit, not responding to verbal cues, no speech, aggressive or self-injurious behavior | Pathologic MRI | 41 | 6 | 32 | Improvement of all symptoms, no hyperactivity, no attention deficit |
3 | Hyperactivity, attention deficit, sustained inappropriate play, compulsive behavior, abnormal speech | Pathologic EEG | 41 | 4 | 33 | Improvement of all symptoms especially in speech, no hyperactivity |
4 | Hyperactivity, attention deficit, not responding to verbal cues, stereotype | Consanguinity | 39 | 3,5 | 30 | Improvement of all symptoms |
5 | Hyperactivity, attention deficit, not responding to verbal cues, no speech, compulsive behavior, preoccupation with parts of objects, sustained inappropriate play | Positive family history | 45 | 4 | 40 | Minimal improvement of all symptoms |
6 | Hyperactivity, attention deficit, no speech, compulsive behavior, sustained inappropriate play | Food intolerance (aggravation of symptoms after carbohydrate ingestion) | 41 | 5 | 37 | Moderate improvement in speech and attention deficit; minimal improvement of remaining symptoms |
See legend to Table 2 for details. Patients were not undergoing adjuvant therapy during ketogenic diet intervention.