Table 2.
Variables in pathology |
Examples |
---|---|
database | |
Patient details |
Name, date of birth, Personal Health Number, geographic location, sex |
Biopsy details |
Date of biopsy, native versus transplant biopsy, surgical case number |
Primary and secondary diagnoses |
As per pathologists’ discretion |
Quantitative pathology details |
Number of glomeruli |
Number of obsolete glomeruli | |
Number of segmentally sclerotic glomeruli Number of glomeruli with crescents | |
Severity of interstitial fibrosis and tubular atrophy | |
Severity of arteriolar and arterial vascular disease | |
Immunofluorescence findings |
0-3+ for each of IgG, IgM, IgA, C3 and C1q |
Disease-specific classifications | IgA nephropathy: MEST score |
Transplant allograft: Banff classification | |
Lupus nephritis: ISN/RPS classification | |
FSGS: Columbia classification | |
ANCA vasculitis: EUVAS classification |
MEST = based on Oxford classification [12]. ISN/RPS = International Society of Nephrology / Renal Pathology Society. FSGS = focal segmental glomerulosclerosis.