Table 2.
Variables stored in PROMIS as part of the provincial pathology database, with representative examples
|
Variables in pathology |
Examples |
|---|---|
| database | |
| Patient details |
Name, date of birth, Personal Health Number, geographic location, sex |
| Biopsy details |
Date of biopsy, native versus transplant biopsy, surgical case number |
| Primary and secondary diagnoses |
As per pathologists’ discretion |
| Quantitative pathology details |
Number of glomeruli |
| Number of obsolete glomeruli | |
| Number of segmentally sclerotic glomeruli Number of glomeruli with crescents | |
| Severity of interstitial fibrosis and tubular atrophy | |
| Severity of arteriolar and arterial vascular disease | |
| Immunofluorescence findings |
0-3+ for each of IgG, IgM, IgA, C3 and C1q |
| Disease-specific classifications | IgA nephropathy: MEST score |
| Transplant allograft: Banff classification | |
| Lupus nephritis: ISN/RPS classification | |
| FSGS: Columbia classification | |
| ANCA vasculitis: EUVAS classification |
MEST = based on Oxford classification [12]. ISN/RPS = International Society of Nephrology / Renal Pathology Society. FSGS = focal segmental glomerulosclerosis.