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ANGPT1 and ANGPT2 mRNA are dysregulated in patients with DN. ANGPT1 and ANGPT2 mRNA expression in isolated glomeruli from patients with diabetic nephropathy and live donor kidney. ANGPT2 is increased in glomeruli obtained from biopsy specimens of patients with DN (n=12) compared with biopsy specimens from live donor kidneys (n=32) (live donor kidney versus diabetic nephropathy, *P=0.00002).
