Table 2.
Epidemiological Characteristics of 76 Episodes of Candida Infection in 35 Patients With Interleukin 12Rβ1 Deficiencya
Characteristics | Episodes, No. (%) |
---|---|
Type of candidiasis | |
Recurrent or persistent | 53 (70)b |
Acute | 23 (30) |
Community acquired | 69 (91) |
Hospital acquiredc | 7 (9) |
Risk factors | |
Antibiotic treatment | 42 (55) |
Immunosuppression | 2 (3) |
Antibiotics plus immunosuppression | 5 (7) |
Neutropenia | 0 |
Comorbid conditionsd | 0 |
Central venous catheter plus antibiotics | 2 (3) |
Abdominal surgery plus antibiotics | 1 (1) |
Esophageal carcinoma plus antibiotics | 1 (1) |
Bone marrow transplantation plus antibiotics | 1 (1) |
No risk factors recorded | 27 (36) |
Candida species | |
Candida albicans | 40 (53) |
Species not identified | 34 (45) |
C. albicans plus other Candida species | 2 (3)e |
Other fungal infections | |
Trichophyton rubrum | 1 (1) |
a The median patient age at onset of first Candida infection ( ± standard deviation) was 1.5 ± 7.87 years.
b When the corresponding physician stated that a patient had multiple episodes of candidiasis, but only 1 episode was noted in the questionnaire, the patient was considered to have recurrent or persistent candidiasis, and only the reported episode was considered in the statistical analysis.
c Candida infections that occurred when the patients were hospitalized were considered probable cases of nosocomial infection.
d Comorbid conditions conferring a predisposition to candidiasis, such as diabetes, renal insufficiency, or pancreatitis.
e Coinfection with C. albicans and Candida glabrata was recorded in 2 episodes.